Centro de Investigación Biomédica - CENBIO
Línea de investigación
- Evaluación de la actividad biológica de extractos de plantas, moléculas de síntesis química y nanopartículas.
- Terapia génica.
- Ingeniería de microorganismos para la producción de biomoléculas de interés biomédico.
Objetivo
Generar conocimiento que aporte al desarrollo de la biomedicina en el país, a través de (I) biodescubrimiento de moléculas con actividad biológica (II) Producción de moléculas de interés biomédico a través de plataformas biológicas.
Integrantes
Linda Guamán (líder)
Linda Guamán (líder)
Linda Guamán (líder)
Saskya Carrera
Rebeca González
Jorge Heredia Moya
Johana Zúñiga Miranda
Arianna Mayorga Ramos
Publicaciones 2023
- CRISPR-CAS-based antimicrobials: Design, challenges, and bacterial mechanisms of resistance
- Current landscape and future directions of synthetic biology in South America
- Current landscape of methods to evaluate antimicrobial activity of natural extracts
- Environmental and nuclear influences on microalgal chloroplast gene expression
- The E1a adenoviral gene upregulates the Yamanaka factors to induce partial cellular reprogramming
- Nude and modified electrospun nanofibers, application to air purification
- Physicochemical characteristics and antioxidant capacity of ecuadorian paramo flowers
Publicaciones 2022
- Protective role of butyrate in obesity and diabetes: New insights
- High—throughput and automated screening for COVID-19
- Evaluation of biological activity of natural compounds: Current trends and methods
- Synthesis and Evaluation of Biological Activities of Schiff Base Derivatives of 4-Aminoantipyrine and Cinnamaldehydes
- Engineering functional thermostable proteins using ancestral sequence reconstruction
- Ancestral sequence reconstruction of a cytochrome P450 family involved in chemical defense reveals the functional evolution of a promiscuous, xenobiotic-metabolizing enzyme in vertebrates
- Complexing the Oncolytic Adenoviruses Ad∆∆ and Ad-3∆-A20T with Cationic Nanoparticles Enhances Viral Infection and Spread in Prostate and Pancreatic Cancer Models
- Diaza-1, 3-butadienes as Useful Intermediate in Heterocycles Synthesis
- Evaluation of the Anti-Leishmania mexicana and –Trypanosoma brucei Activity and Mode of Action of 4,4′-(Arylmethylene)bis(3-methyl-1-phenyl-1H-pyrazol-5-ol)
- Synthesis, Experimental and Theoretical Study of Azidochromones
- Synthesis of 4-Arylallylidenepyrazolone Derivatives
Contacto
Directora: Dra. Linda Guamán. PhD en Microbiología.
Dirección: UTE Occidental, Av. Mariscal Sucre s/n y Mariana de Jesús
Teléfono: (02) 2 990 800, ext. 2115
Correo: linda.guaman@ute.edu.ec
